I will soon be applying for German student VISA on the 9th of september.
Apart from the regular procedure in Mumbai, India of the checklist, do you recommend me taking care fo somethings so I don't end up with a refusal.
My profile is: 10th(IGCSE-Cambridge board)- 65% agg
12th(A levels-Cambridgee Board)- 45% agg
I have taken up bachelor's degree in Berlin which is International Business Administration- focus of E-business.

Pleaase note: I had Commerce related subjects in my 10th grade but not my 12th grade. I have always had computers as my subjects throughout my years.
Do you think that a change in course can result in a rejection? Also, do you think that low scores will affect my application? Please let on me some light.

I think you have to thoroughly justify your motivation to pursue studies in Germany.. A typical question (especially for an Undergraduate courses is): Why not in India, why in Germany ? 

Have you already completed a bachelor's degree? If not, you do not seem to meet the formal requirements for admission to a German university. 

I have already got admission into a private university of applied sciences. Admission is not my query. Getting the student VISA on first attempt is. I m just trying to figure out how do I explain a change in the course.

Thanks, yess I m trying to figure out how to explain on that question.